A closed-loop supply chain model incorporating government involvement has been developed to optimize the utilization of waste products, quantifying the quality level of such products.The utilization of game theory within the model allows for an examination of how government incentives and penalties for remanufacturing impact pricing decisions withi
Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting
Summary: Mitochondrial dysfunction causes muscle wasting in many diseases and probably also during aging.The underlying mechanism is poorly understood.We generated transgenic mice with unbalanced mitochondrial protein loading and import, by moderately overexpressing the nuclear-encoded adenine nucleotide translocase, Ant1.We found that these mice p
Breast milk vs. non-nutritive sucking to reduce pain from minor invasive procedures in neonates
Background Neonates undergo many uncomfortable, invasive minor procedures during their first hospital stay.Nonpharmacological interventions may provide valuable alternatives for pain relief in neonates during minor procedures.Objective To compare the analgesic effect of orally administered breast milk vs.non-nutritive sucking (NNS) in neonates who
Chemical Diversity of Fuzhuan Brick Teas from Hunan and Shaanxi
This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick Hard Good tea and to identify the metabolites from fungi in Fuzhuan brick tea.Metabolomic studies on fresh tea leaf sa
Experiences of social support among women presenting for obstetric fistula repair surgery in Tanzania
Alexis C Dennis1 Sarah M Wilson1–3 Mary V Mosha4 Gileard G Masenga4 Kathleen J Sikkema1,5,6 Korrine E Terroso1 Melissa H Watt1 1Duke Global Health Institute, Duke University, 2Department of Veterans Affairs, Mid-Atlantic Mental Illness Research, Education and Clinical Center, 3Durham Veterans Affairs Medical NO-POO DECADENCE Center, Durham, N